TWiV explains how liquid–liquid phase separation and a phage-encoded inhibitor cooperatively drive transcriptional transition during phage SPO1 infection, and the first smallpox virus genomes from an early outbreak in South America. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Fred Murphy, a pioneer in virology (J Virol) New midge-borne orthobunyavirus sickening cattle in Europe (Science) What to Know About the Vaccines Targeted by Trump’s Executive Order (NY Times) What vaccine Executive Order gets wrong (CIDRAP) Trudy Rey’s 100th post at virology blog Transcriptional transition during phage SPO1 infection (Nucl Acids Res) Phase separation 101 (Iwasa lab) Early smallpox in America (Science) Letters read on TWiV 1349 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – APod August 7: Rubin’s Cosmos Field Rich – Jenner’s Inquiry  Original, “annotated”;  (PDF) Smallpox vaccination and opposition by anti-vaccination societies in 19th century Britain Jolene – Scott Seligmann’s web tool for searching keywords in podcast transcripts  Vincent – The End of Reading is Here Listener Picks Tony – Fauci Fiasco Addendum Charles – The Proposed Changes in Childhood Vaccination: A Strongly Felt Opinion Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.