An Australian man used ChatGPT, Grok, and AlphaFold to design a personalized mRNA cancer vaccine for his dying dog, and the tumor shrank by half. Hunter and Daniel also cover using Claude for post-op medical notes, Karpathy's auto research agents beating a human expert by 11%, and why Philips calling a questionnaire a "conversational virtual assistant" is a war crime.

Why Meta Killed the Metaverse (And is Failing at AI)

They Might Be Self-Aware is a twice-weekly AI podcast about the week's news, tech, and culture, and the question in its name: are the machines becoming self-aware?

Every episode starts with a real story. A new Claude or ChatGPT release, an AI lawsuit, the Pope's verdict on machine souls, Martin Scorsese making films with AI. Then it chases that story somewhere stranger, funnier, and more human than the headline. This is AI as a culture story, not a tech beat: the relief of finally hearing people who are as deep in it as you are.

Hunter Powers and Daniel Bishop host. Two guys who actually build with this stuff, arguing about it fast, funny, and unfiltered, not reading you benchmarks or "10 prompts to save you time." Gary produces, phoning in the cold open from a payphone. He has no last name, and a backstory no one on staff has managed to verify. One of the hosts might not be human. We won't say which.

New episodes Mondays and Thursdays, from The Blur. theblur.ai