The Trip Lab
The Trip Lab
Dr. Mary Ella Wood
#22 – Is Modern Medicine Still Evidence-Based? Reclaiming Evidence, Restoring Clinical Wisdom
35 minutes Posted Feb 2, 2026 at 12:00 pm.
What Do We Mean by Evidence-Based Medicine?
How COVID Played a Role
Statistical Significance vs. Clinical Meaning
When Surrogate Endpoints Miss the Bigger Picture
Who Gets Studied and Who Gets Excluded
Reductionism and the Limits of Modern Medical Models
Guidelines, Consensus, and Clinical Judgment
Curiosity, Harm, and Restoring Clinical Wisdom
The Trip Lab: Exploration and the Future of Medicine
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Show notes
Is modern medicine still evidence-based, or have we quietly mistaken rigor for certainty? Evidence-based medicine is essential. It’s why we save lives, advance care, and trust modern healthcare. But as medicine has become more specialized and disease more complex, something subtle has happened. Rigor has increasingly turned into reductionism, and evidence is often applied in ways that don’t fully match the realities of clinical practice or patients’ lived experiences. In this episode of The T...