The Stem Cell Podcast Podcast
The Stem Cell Podcast
The Stem Cell Podcast
Ep. 287: “Blood Development” Featuring Drs. Andrew Elefanty and Elizabeth Ng - episode of The Stem Cell Podcast podcast

Ep. 287: “Blood Development” Featuring Drs. Andrew Elefanty and Elizabeth Ng

1 hour 29 minutes Posted Feb 4, 2025 at 8:00 pm.
Heart Repair – An engineered epicardial engineered heart muscle allograft remuscularized a human heart.
Causes of Preimplantation Failure – Single-embryo proteomics of poor-quality embryos provided insights into preimplantation development failure.
Imprinting Abnormalities in Mammals – Researchers targeted imprinting abnormalities at their source — embryos from same-sex parents.
Temperature-Controlled Cell Fate – Melt is a protein that reversibly clusters and translocates to the membrane in response to small temperature changes.
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Show notes
Guests:
Drs. Andrew Elefanty and Elizabeth Ng are Senior Principal Investigator and Principal Investigator, respectively, at the Murdoch Children’s Research Institute. In the Blood Development group, they aim to develop innovative cellular therapies for blood and  cartilage-related diseases. They talk about their recent study deriving and transplanting HSCs, their work on reporter lines, and their collaborative lab setup.
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The Stem Cell Science Round Up
Heart Repair – An engineered epicardial engineered heart muscle allograft remuscularized a human heart. (
2:04)
Causes of Preimplantation Failure – Single-embryo proteomics of poor-quality embryos provided insights into preimplantation development failure. (
14:57)
Imprinting Abnormalities in Mammals – Researchers targeted imprinting abnormalities at their source — embryos from same-sex parents. (
25:54)
Temperature-Controlled Cell Fate – Melt is a protein that reversibly clusters and translocates to the membrane in response to small temperature changes. (
35:47)
Image courtesy of Drs. Andrew Elefanty and Elizabeth Ng
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