The Skin Report
The Skin Report
Dr. Simran Sethi
Tranexamic Acid: How to Use It for Hyperpigmentation
8 minutes Posted Jun 11, 2025 at 9:00 am.
Intro: Why Tranexamic Acid Matters
What Is Tranexamic Acid & How It Works
Tranexamic Acid vs. Hydroquinone
Combining Tranexamic Acid with Other Ingredients
Why You Also Need Retinol 
Skin Barrier Repair is Key
Importance of Sunscreen & Blue Light Protection
Oral Tranexamic Acid for Melasma
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Show notes

In this episode of The SKIN Report, Dr. Simran Sethi takes a deep dive into tranexamic acid, a powerful and increasingly popular ingredient for treating hyperpigmentation.

Learn what tranexamic acid is, how it works to reduce melanin production, and why it’s considered a safer alternative to hydroquinone. Dr. Sethi explains how to pair it with other ingredients like retinol, moisturizer, and sunscreen for best results—and what makes it effective for melasma but not post-inflammatory pigmentation or sunspots.

👉 Whether you’re new to tranexamic acid or looking to optimize your routine, this episode offers clear, science-backed guidance on getting real results.

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