Spray drying has become one of the go-to techniques for the manufacture of amorphous dispersions and inhalable formulations due to the ability to control solvent content, morphology, size, and density of the resulting particulates in the dried powder. 

X-ray computed tomography is a new technique for this spray dried dispersion application. 

Peter Oberta, Managing Director at Rigaku, co-authored the study on this new approach and he joins the show to explain everything you need to know. 

We discuss: 

- The advantages of using this technique 

- How to control particle size, morphology, and density using x-ray CT 

- How much sample preparation is necessary for x-ray CT 

- The qualitative results of the study 

- The resolution that can be achieved with x-ray CT 

- The data treatment required to complete the analysis 

Mentioned during the podcast: 

- Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography  

- X-Ray CT Imaging 

- DigiM 

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