115 Broadway, Cambridge Biogen, founded in 1978, was the first biotechnology company in Cambridge, and in many ways, it created the mold for the life science businesses that dominate Kendall Square to this day. The company exploits fundamental insights into gene and protein expression to design monoclonal antibodies and other medicines for the treatment of neurological and neuromuscular diseases, hematologic diseases, and cancer. Its Cambridge campus includes this facility at 115 Broadway as well as its world headquarters office at 225 Binney Street.  Guest speakers Phillip Sharp, Institute Professor emeritus, Department of Biology and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Co-founder, Biogen; Nobel Prize winner, 1993 Walter Gilbert, Professor, Department of Molecular and Cellular Biology, Harvard University; Co-founder, Biogen; Nobel Prize winner, 1980

Internet Accelerator

Welcome to the official audio companion to the Innovation Trail, a walking tour in Boston and Cambridge, Massachusetts that takes you across roughly two miles of dense urban streetscape and 400 years of scientific, technical, medical, and entrepreneurial advances. With the help of guide and narrator Carmichael Roberts and a galaxy of guest experts and tech celebrities, you'll learn about the people, ideas, and inventions — from the telephone to messenger RNA vaccines — that have long set Boston and Cambridge apart as world capitals of innovation.

Most visitors start walking the Innovation Trail at 30 School Street in Boston, near the Park Street T stop. If you're accessing this guide through a podcast player, you'll see that the segments start there with "Patent Pioneer" and proceed west to Cambridge. (See http://theinnovationtrail.org for an interactive map.) But you can also begin the Trail from the Cambridge side, at 810 Main Street, and start with "The Last Candy Factory" episode and go in reverse order! 

The names of each stop on this guide correspond to those on our website, so you can also start the Trail at any stop, and walk as much as you have time for. The Trail includes four museums with regular operating hours, and we encourage you to stop in and explore any of them that pique your interest.

Produced by Wade Roush: https://www.waderoush.com