Psychiatrist Richard A. Friedman explains how a rare genetic mutation affecting the enzyme FAAH, and a ubiquitous neurotransmitter called Anandamide may account for unusually low anxiety, reduced drug cravings, and an innate buoyancy, the type of which you might find in a daily podcast host. Plus, Louisville reverses its immigration detainer policy under federal pressure, reigniting the debate over sanctuary cities and local autonomy. And in the Spiel a burial standoff concerning the former President of Zambia.

Produced by Corey Wara

Production Coordinator Ashley Khan

Email us at ⁠⁠⁠⁠[email protected]⁠⁠⁠⁠

To advertise on the show, contact ⁠⁠⁠⁠[email protected]⁠⁠⁠⁠ or visit ⁠⁠⁠⁠https://advertising.libsyn.com/TheGist⁠⁠⁠⁠

Subscribe to The Gist: ⁠⁠⁠⁠https://subscribe.mikepesca.com/⁠⁠⁠⁠

Subscribe to The Gist Youtube Page: ⁠⁠⁠⁠https://www.youtube.com/channel/UC4_bh0wHgk2YfpKf4rg40_g⁠⁠⁠⁠

Subscribe to The Gist Instagram Page: ⁠⁠⁠⁠GIST INSTAGRAM⁠⁠⁠⁠

Follow The Gist List at: ⁠⁠⁠⁠Pesca⁠⁠⁠⁠ ⁠⁠⁠⁠Profundities | Mike Pesca | Substack⁠⁠⁠⁠