Drinking feels harmless for many of us. For others, alcohol is also a powerful substance that changes the way the brain processes reward and emotion. Dr. Charles Knowles says a drinking habit that starts as a way to relax or connect with others can gradually become much harder to manage. We discuss the neuroscience of alcohol, why some people are more vulnerable to dependence and how genetics influence our relationship with drinking. Charles also shares insights from his own recovery and why understanding alcohol may help reduce shame and stigma.