Show notes
Our guest today is Dr. Lilianne Mujica Parodi, the director of the Laboratory for Computational Neurodiagnostics at Stony Brook University.We will be talking to Lily about her paper in PNAS last year that revealed neurobiological changes associated with aging can be seen in a person’s late 40s, a much younger age than what was previously thought. She and her colleagues at Stony Brook also found that this process may be prevented or even reversed based on dietary changes that involve minimizing the consumption of simple carbohydrates. The study’s targeted experiments showed that the biomarker for brain aging could be reliably modulated with consumption of different fuel sources. The study showed that decreasing glucose and increasing ketones resulted in the stability of brain networks.Much of Lily’s work over the years has been focused on developing neuroimaging tools. In today’s interview, we talk to her about functional magnetic resonance imaging, also known as fMRI, which measures the small changes in blood flow that occur with brain activity. It may be used to examine the brain’s functional anatomy, evaluate the effects of stroke or other disease, and even guide brain treatment. Functional magnetic resonance imaging also can detect abnormalities within the brain that cannot be found with other imaging techniques.Show notes:[[[[[[[[[[[[[00:45:59] Ken asks about Lily’s 2016 paper published in the Frontiers of Neuroscience journal, that ran under the title, “Signal Fluctuation Sensitivity: An Improved Metric for Optimizing Detection of Resting-State fMRI Networks.”[[[[00:59:33] Ken asks about Lily’s 2019 paper in PNAS, titled, “Diet Modulates Brain Network Stability, A Biomarker for Brain Aging, in Young Adults.” Lily explains how this study was conducted and what its results were.[[[[[[

