Simply Oncology
Simply Oncology
John McGrane & Michael Rowe
Episode 22: In the Clinic - Discussing molecular profiling in endometrial cancer with Dr Angela George
33 minutes Posted Oct 11, 2024 at 7:00 am.
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In recent years we have seen a marked change in the landscape of treatment for endometrial cancer.
This has been driven by understanding the different molecular subtypes of endometrial cancer.
POLE - with an excellent prognosis
MMR deficient - with good prognosis and option for immunotherapy
No Specific molecular profile - intermediate outcome and work still to be done
P53 mutant - with a poorer outcome

Dr Angela George from the Royal Marsden Hospital has a specialist interest in genomics and shares her expertise and knowledge on this fascinating area of gynaecological cancers.