Global incidence of venous thromboembolism (VTE) is between 1 and 2 per 1,000 adults annually. In this podcast Dr Thomas Round, EKU Clinical Lead discusses with Dr Nicholas Jones, a salaried GP, GP Cardiologist and a Wellcome Trust Doctoral Research Fellow at the University of Oxford, the diagnosis, management and thrombophilia testing of venous thromboembolic diseases including the changes in the approach to assessment recommended by NICE and how the new guidelines have adjusted their recommendations around anticoagulation treatment.