Raising Biotech
Raising Biotech
Surani Fernando
S2, E3: Ray Therapeutics leveraging optogenetics to tackle vision loss with CEO Paul Bresge and Dr José-Alain Sahel (University of Pittsburgh)
33 minutes Posted May 28, 2024 at 11:04 am.
Partner segment: Mindgram.ai
Background of Ray Therapeutics and focus on late-stage retinal diseases
CEO Paul Bresge's backstory, personal motivations to enter the biotech world
Formation of Ray Therapeutics in 2021 with Co-founder and Chairman Sean Ainsworth
Leveraging breakthrough science from inventor and optogenetics pioneer Dr Zhuo-Hua Pain
How Ray was able to attract investors and secure an oversubscribed $100m Series A
Dr José-Alain Sahel gives his take on Ray's early data and scientific potential
Ray's plans to get the drug into Retinitis Pigmentosa patients and regulatory pathway
Safety benchmarks and meaningful efficacy outcome measures
Optogenetics competitive landscape and Ray's potential edge
Future financing goals and the company's longer term vision
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Show notes
In this episode of Raising Biotech, Surani explores the fascinating world of vision restoration and optogenetics with Ray Therapeutics. The company raised an oversubscribed $100m Series A in May 2023, which was particularly noteworthy during a extremely grim year for fundraising. Surani speaks with CEO and Co-Founder Paul Bresge about how his daughter's retinitis pigmentosa diagnosis drove him to enter the biotech world. He discusses meeting Co-founder Sean Ainsworth and seeing groundbreaking experiments in blind mice from inventor Dr Zhuo-Hua Pan that lead to the formation of Ray. He also talks about what drew investors to Ray's mission, its clear regulatory path forward (first in retinitis pigmentosa patients followed by Stargardt disease and geographic atrophy) and visions for the company's future. Surani is also joined by renowned optogenetics leader Dr José-Alain Sahel, Distinguished Professor, Department of Ophthalmology, University of Pittsburgh School of Medicine, to talk about Ray's scientific foundations, early data, theoretical safety/efficacy profile and potential to make a meaningful impact in late-stage retinal disorder patients with close to no vision.
Timestamps:
This episode is partnered with Mindgram.ai, a research tool powered by AI to better serve the biopharma community. Listeners of the Raising Biotech podcast are able to get an exclusive free trial of Mindgram via this link, using the code: raisingbiotech24
For any comments, questions, feedback or suggestions you can connect directly with Surani Fernando on LinkedIn or email: [email protected]
Music composed by: Yrii Semchyshyn (Coma Media)
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