For children with a history of penicillin allergy, new evidence suggests a vast majority of kids could be “de-labeled” after undergoing a risk assessment and oral challenge in the pediatric emergency room. George Hoganson, MD, a Washington University emergency medicine fellow at St. Louis Children’s Hospital, is collaborating on a two-year, multi-center study to test children described as penicillin allergic, but who very likely do not have a true penicillin allergy in the St. Louis Children's Hospital Emergency Department.

Dr. Hoganson joins the show to discuss the study, which involves a penicillin oral challenge with observation in the Children’s emergency room.