Kansas City Chiefs vs. Buffalo Bills NFL Pick Prediction 11/2/2025 by Tony T. Chiefs at Bills Injuries KC running back Pacheco and left tackle are out with a questionable right guard. Their defensive starters are healthy. Buffalo receiver Palmer is out. On defense a tackle is out with nickel back questionable. The Chiefs have a clear injury advantage based on the Chao ratings. Buffalo has a low defensive rating at 68.5 based on their players on the IR. KC defense has the healthiest rating at 92.7.