Penn Talks Science
Penn Talks Science
Penn Science Policy and Diplomacy Group
“A Misfolding Misfortune” A Sci-Comm inspired D&D Playthrough: Episode 1
1 hour 28 minutes Posted Oct 31, 2025 at 4:03 pm.
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Welcome, science adventurers!


In episode 1 of this mini-series, we begin a playthrough of PSPDG’s SciComm Dungeons & Dragons adventure about neurodegenerative disease, “A Misfolding Misfortune”, written by Dimitris Boufidis, Freddy S. Purnell, Tammy Ray, David Sidibe, and Amanda N. Weiss.


The module is available for free here: https://www.pspdg.com/ttrpgs/2025/1/7/a-misfolding-misfortune-dampd-5e-adventure-about-neurodegenerative-disease


In this actual play, Amanda N. Weiss runs the adventure for players Diego Mendez, Gabriel Vega-Bellido, Miles Arnett, and Joseph McGaunn.


Music Credits:

Danse Morialta Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 Licensehttp://creativecommons.org/licenses/by/3.0/


Heart of Nowhere Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 Licensehttp://creativecommons.org/licenses/by/3.0/


Ancient Mystery Waltz (Presto) Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 Licensehttp://creativecommons.org/licenses/by/3.0/


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