PCE
PCE
Practicing Clinicians Exchange
A Nursing Perspective on PARP Inhibitors in Prostate Cancer
11 minutes Posted Jun 30, 2022 at 12:00 pm.
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Show notes

In this episode, Brenda Martone, MSN, ANP-BC, AOCNP describes recent evidence on PARP inhibitor therapy in metastatic castrate-resistant prostate cancer (mCRPC) and discusses best practices for incorporating PARP inhibitors into clinical practice. Topics include:

  • An overview of the PROpel study of olaparib and the TRITON study of rucaparib
  • FDA-approved indications for olaparib and rucaparib
  • Genetic and molecular testing for BRCA1/2 and other HRR mutations
  • Managing adverse events associated with olaparib and rucaparib
  • Monitoring for and managing anemia
  • Gastrointestinal side effects
  • Fatigue
  • A look at the future of PARP inhibitors in mCRPC with combination approaches of AR-directed therapy and PARP inhibition

Presenter:
Brenda Martone, MSN, ANP-BC, AOCNP
Nurse Practitioner
Division of Genitourinary Oncology
Northwestern Medicine
Chicago, Illinois

Link to full program:
PCE.is/Onc22