Neurology Minute
Neurology Minute
American Academy of Neurology
The DRAIN Trial
3 minutes Posted Jul 15, 2026 at 8:30 am.
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Dr. Margarita Fedorova discusses the DRAIN trial and the efficacy of acetazolamide in idiopathic normal pressure hydrocephalus. 

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Virhammar J, Fasth O, Ekblom M, et al. Safety, tolerability, and efficacy of acetazolamide in idiopathic normal pressure hydrocephalus (DRAIN) in Sweden: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol. 2026;25(6):550-559. doi:10.1016/S1474-4422(26)00126-2