Discover the truth about population-wide NAD+ optimization with Dr. Jin-Xiong She from Jinfinity Precision Medicine. We break down the clinical flaws behind the recent Janssen and Houtkooper human blood study claiming NAD levels do not decline with age or lifestyle habits. Learn how ethnicity, health status, NMN vs. NR synergies, and high-dose niacin vascular inflammation impact intracellular biomarkers, and discover the true optimal blood reference target for healthy aging.
Does human NAD+ actually decline with age, and do popular precursors like NMN or NR work for everyone? In this episode of Modern Healthspan, we sit down with clinical frameworks pioneer Dr. Jin-Xiong She, founder of Jinfinity Precision Medicine, to dissect recent human trial publications. Dr. She critiques a controversial recent paper asserting that blood NAD+ remains static across age groups, exposing its narrow testing intervals and misleading over-generalizations. Drawing from thousands of independent patient datasets, Dr. She details the sharp, non-linear NAD drop off that occurs between ages 20 and 30, while revealing the hidden impacts that ethnicity and background health status have on your baseline cellular metrics. We also explore the optimal human blood target range, shifting from a baseline of 40 µmol to a clinical sweet spot between 55 and 80 µmol, and highlight the surprising cardiovascular inflammation risks linked to over-supplementing with high-dose niacin
🌐Links in this video
https://www.jinfiniti.com/
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