In this episode, I have a fascinating conversation with Dr. Michelle Ploughman. Michelle is an Associate Professor in the Faculty of Medicine at Memorial University. She is an expert in studying the effects of exercise on brain plasticity and her research focuses on the effects of exercise, rehabilitation and lifestyle habits on the brain challenged by injury, disease and aging. We talk about exercise prescription in multiple sclerosis (MS). We start discussing what we know about the risk factors of MS, and the gaps in knowledge in the prescription of exercise for these patients. We then talk about the importance of controlling body temperature during exercise and how essential it is to adapt training in periods where the symptoms of the disease are exacerbated. I found this episode extremely informative and educational. You can see what Michelle is working on on twitter @michploughman.