Iron Culture presented by MASS
Iron Culture presented by MASS
MASS Research Review
Ep 333 - Are High-Protein Diets Really Harmless?
1 hour 34 minutes Posted Jun 25, 2025 at 9:06 am.
Intro3:00 Helms’ new article about the purported harms of high-protein diets19:25 Claim 1 – protein reduces lifespan27:48 Claim 2 – protein makes bones weaker43:38 Claim 3 – protein harms kidneys50:53 Claim 4 – protein causes diabetes57:22 Trex’s social media beefs – keto and seed oils1:03:40 Types of observational studies1:08:35 Seeking truth versus defending biases1:17:32 Limitations versus fatal flaws1:24:19 Limitations of RCTs (randomized controlled trials)1:32:23 Wrapping up
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Show notes
In this episode of Iron Culture, Dr. Eric Helms talks about his forthcoming article in the MASS Research Review covering the purported harms of high-protein diets. This isn’t your typical oversimplified dunk-fest that readily dismisses concerns about high-protein diets. Instead, Helms reviews a thorough paper that reviews common concerns in detail and assessed their plausibility in an objective manner. The claims include: Claim 1 – protein reduces lifespanClaim 2 – protein makes bones weakerClaim 3 – protein harms kidneysClaim 4 – protein causes diabetesAfter that, Dr. Eric Trexler discusses a recent Instagram thread that pulled him into arguments against his will. The post was about his recent article on ketogenic diets and seed oils – two topics that are always bound to attract some controversy and heated debate. This conversation discusses the strengths and limitations of different types of scientific research and also touches on bias, objectivity, and the process of seeking the truth with an open mind.Time stamps:0:00 Intro3:00 Helms’ new article about the purported harms of high-protein diets19:25 Claim 1 – protein reduces lifespan27:48 Claim 2 – protein makes bones weaker43:38 Claim 3 – protein harms kidneys50:53 Claim 4 – protein causes diabetes57:22 Trex’s social media beefs – keto and seed oils1:03:40 Types of observational studies1:08:35 Seeking truth versus defending biases1:17:32 Limitations versus fatal flaws1:24:19 Limitations of RCTs (randomized controlled trials)1:32:23 Wrapping up