Enola Holmes 2 is a sequel to the 2020 film Enola Holmes. The young adult oriented mystery features Enola, the younger sister of famous detective Sherlock Holmes, as she struggles to find clients for her new detective agency.

The movie, which premiered in November 2022 on Netflix, stars Millie Bobby Brown as Enola, and Henry Cavil as her older brother Sherlock. Other cast members include Helena Bonham Carter and David Thewlis.