📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.Today, I’m joined by the incredible Dr. Nora Abdul-Hussein, a physician-scientist, medical geneticist, and one of the leading voices in the field of genomic medicine. In this episode, Dr. Abdul-Hussein and I dig into a huge question—why do two people taking the exact same GLP-1 medication have such wildly different results, from weight loss to side effect profiles? She shares her unique path from internal medicine to cutting-edge population genomics, and how her work at 23andMe is beginning to answer some of medicine’s toughest puzzles.Episode Timestamps:Introduction: podcast focus on genetics, peptides, and longevity ... Dr. Nora Abdul-Hussein’s background and journey in genomic medicine ... Prevention and population-scale genetics ... Power of genetic insights for personal lifestyle choices ... Barriers to adopting genetics in clinical practice ... Pharmacogenomics and the move toward personalized prescribing ... Launching a large-scale study on GLP-1 genetics ... Discovery: GLP-1 receptor gene variants linked to weight loss and nausea ... Risk calculators and personalized expectations for GLP-1s ... Broader genomics: diet, exercise, and response variability ... Avoiding genetic determinism and emphasizing holistic care ... Findings for tirzepatide and the GIP receptor ... Population differences and ancestry’s impact on results ... Is genetic information ready for prime time in GLP-1 therapy? ... Clinical implications beyond “calories in, calories out” ... GLP-1s: potential for non-weight related conditions ... Personalized medicine: integrating genomics with other data ... Reducing shame and embracing genes as tools for prevention ... Genomic information as an empowering health strategy ... Study insights and validation: self-reporting and sample diversity ... Protecting privacy and building trust in genomics ... Final thoughts: embrace your genes and use the data for healthspan ... Where to learn more and wrap-up ... Our Amazing Sponsors:Mitopure Gummies by Timeline – Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A—without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/NAT20 to get Mitopure starting at just $99 and save an additional 20% on your order.Manukora Honey – A delicious real-food source of prebiotics, Manukora's high-MGO Manuka honey helps support your gut microbiome, digestion, and immune health with just one teaspoon a day. Head to MANUKORA.com/NAT to save up to 31% plus receive $25 worth of free gifts with the Starter Kit.Just Thrive 90-Day Probiotic – A spore-based probiotic that survives stomach acid to arrive 100% alive in your gut, supporting better digestion, nutrient absorption, immunity, and less bloating. Start your first 90-day subscription today and you'll get a FREE 90-day supply of Digestive Bitters (a $90 value) to help optimize digestion and support healthy appetite regulation. Click HERE to learn more.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterOriginal InstagramBackup InstagramDr. Bill Lawrence Episode