My guest today is Andy Lee who is the Chief Operating Officer at Vincere Biosciences. Vincere is working to stop Parkinson’s disease by creating small molecules or drugs that target mitochondrial dysfunction. There is increasing evidence that a dysfunctional mitochondria can lead to the onset of Parkinson’s disease. In today’s conversation, we discussed the science behind a dysfunctional mitochondria and mitophagy, the relationship between the mitochondria and Parkinson’s disease, and whether certain mitochondria boosting supplements like Urolithin A and Coq10 that delay the onset of Parkinson’s. We also discussed the biological simulation and computational biology platform used by Vincere - they use AI systems that can be used to screen drugs & targets and simulate cell environments. Finally, we spoke about the challenges with running a biotech company.   Andy comes from a background in technology and computer science background and he combined it with biology to create Vincere Biosciences.All platforms / Episode Show Notes: https://livelongerworld.substack.com/p/alee Find the previous podcast episodes & subscribe to be notified: https://www.livelongerworld.com/podcast Sign up for Premium Subscriber Summarized Show Notes on Key Points: https://www.livelongerworld.com/premium Support on Patreon: https://www.patreon.com/livelongerworldOne-Time support: https://www.paypal.com/paypalme/livelongerworld ANDY LEE / VINCERE BIO LINKS: Vincere Website: https://vincerebio.com/Andy Lee Twitter: https://twitter.com/andy_d_leeLIVE LONGER WORLD LINKS: Website: https://www.livelongerworld.com/Twitter: https://twitter.com/livelongerworldNewsletter: https://livelongerworld.substack.com/Instagram: https://www.instagram.com/longevityfuture/Patreon page: https://www.patreon.com/livelongerworldPodcast All Platforms: https://anchor.fm/livelongerworldYouTube: https://www.youtube.com/c/LiveLongerWorldApple Podcasts: https://apple.co/3eZAoApSpotify: https://spoti.fi/3eZB6O5Google Podcasts: https://bit.ly/3HN0keGPremium Subscriber Benefits: https://www.livelongerworld.com/premiumTIMESTAMPS: Want Summarized Notes on Key Points Discussed in the Podcast? Gain access by signing up as a premium subscriber. Your contribution supports my work and the advancement of longevity science!   Key points summarized in the show notes for premium subscribers include: 1. The connection between Mitochondrial quality control & Parkinson’s disease 2. Mitophagy and the science behind targeting the mitochondria 3. Overview of the Biological Simulation Platform used by Vincere Bio 4. Can compounds like Urolithin A & Coq10 that target the mitochondria delay Parkinson’s 5. Challenges with running a Biotech Co.Learn more on Premium Subscriber Benefits: https://www.livelongerworld.com/premiumEp. Show notes: https://livelongerworld.substack.com/p/alee