My guests in today's episode are Dr. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. Their groundbreaking research focuses on tissue rejuvenation via plasma dilution and heterochronic parabiosis, where the Conboys took a young mouse and an older mouse and sutured them together, such that the animals shared blood and environment. The old mice became rejuvenated & younger. They’ve also pioneered a process called the Neutral Blood Exchange or Therapeutic Blood Exchange, through which dilution of old blood plasma can lead to true rejuvenation in the brain & other tissues of mice to a younger state!!   Further, we touch upon Irina's work showing how decreased Oxytocin levels with age contributes to poor muscle function. Their research is incredibly exciting and we discuss all about it in today’s episode.  Episode Show Notes: https://livelongerworld.substack.com/p/rejuvenation-via-plasma-dilutionSign up for Premium Subscriber Extensive Show Notes & Transcripts: https://www.livelongerworld.com/premium Find the previous podcast episodes & subscribe to be notified: https://www.livelongerworld.com/podcast DR. CONBOY LINKS: Berkeley Lab: https://conboylab.berkeley.edu/  2021 Paper Plasma Dilution Improves Cognition and attenuates neuroinflammation in old mice: https://pubmed.ncbi.nlm.nih.gov/33191466/  2020 Paper Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288913/  2014 Paper Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration: https://www.nature.com/articles/ncomms5082  LIVE LONGER WORLD LINKS: Website: https://www.livelongerworld.com/Twitter: https://twitter.com/livelongerworldNewsletter: https://livelongerworld.substack.com/Instagram: https://www.instagram.com/longevityfuture/Podcast All Platforms: https://anchor.fm/livelongerworldPatreon: https://www.patreon.com/livelongerworldYouTube: https://www.youtube.com/c/LiveLongerWorldApple Podcasts: https://apple.co/3eZAoApSpotify: https://spoti.fi/3eZB6O5 Google Podcasts: https://bit.ly/3HN0keGTIMESTAMPS: Thanks for listening & if you enjoy the episode, please like, subscribe & share! Stay in good health - Aastha.