In this week’s episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. They share the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine. Given the abundance of data available, a special focus is placed on the NAD precursors nicotinamide riboside and nicotinamide mononucleotide. Known mechanisms, limitations, and/or side effects associated with these molecules are additionally highlighted.Correction and clarification: At time point Thank you to our sponsors: Athletic Greens - https://athleticgreens.com/sinclair InsideTracker - https://insidetracker.com/sinclair Levels - https://levels.link/sinclairOur Patreon page: https://www.patreon.com/davidsinclair Lifespan book: https://amzn.to/3sUqurTDr. David Sinclair Social: Instagram Twitter FacebookTo stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.Matthew LaPlante's Social: TwitterTimestamps:(((((((((((((((((((((For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan.