<p>Drs Stuart Spechler and Peter Kahrilis discuss GERD and esophagitis--how they occur and how they are treated. Dr Spechler also discusses a new hypothesis regarding how reflux esophagitis is caused that differs from the traditional teaching that acid and pepsin reflux into the esophagus and burn the mucosa layers.</p> <p>Related articles: <a href= "http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.2016.5657"> Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes</a> <a href= "http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.2016.5827"> Turning the Pathogenesis of Acute Peptic Esophagitis Inside Out</a></p>

Neighborhood Walkability, Weight, and Diabetes

Go beyond the latest discoveries with nuanced, in-depth conversations in Healthy Dialogue, a podcast from the JAMA Network. Host and JAMA Senior Editor, Derek C. Angus, MD, MPH, sits down with the world's leading experts to explore the most pressing issues in health and health care.