The third in a series about the beneficial effects of Ashwagandha, this episode looks at the anti-stress and adaptogenic effects of this incredible herb. Ashwagandha helps improve neuronal plasticity and regeneration, and reduces the damage and death of these cells. To accomplish this effect, ashwagandha triggers the upregulation of HSP70 proteins. Let's review.
URL list from August 3, 2023
Pharmaceutics | Free Full-Text | Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review
https://www.mdpi.com/1999-4923/15/4/1057
Evidence-Based Efficacy of Adaptogens in Fatigue, and Molecular M...: Ingenta Connect
https://www.ingentaconnect.com/content/ben/ccp/2009/00000004/00000003/art00004
Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895966/#:~:text=Heat%20shock%20protein%2070%20(Hsp70)%20is%20a%20molecular%20chaperone%20that,or%20aggregation%20until%20conditions%20improve
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Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0091305703001102
Phytotherapy Research | Medicinal Chemistry Journal | Wiley Online Library
https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.858
Frontiers | c-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer’s Disease
https://www.frontiersin.org/articles/10.3389/fphar.2015.00321/full
Frontiers | DAF-16/FOXO Transcription Factor in Aging and Longevity
https://www.frontiersin.org/articles/10.3389/fphar.2017.00548/full
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