Following on from last week's episode on "toxicity", we are delighted today to welcome back two great friends of GU Cast from the world of radiation oncology - ASTRO President Dr Neha Vapiwala (University of Pennsylvania), and European Urology Associate Editor, Dr Amar Kishan (University of California, Los Angeles). We go through Amar and Neha's letter to the editor following the recent paper in Eur Urol Oncol from the IRRADIATE registry, and dive into the opportunities we have working ...