Cirrhosis represents the end stage of chronic liver injury, characterised by fibrosis and regenerative nodules that disrupt normal liver architecture. While the liver can compensate for years, patients often remain asymptomatic until complications such as ascites, variceal bleeding or hepatic encephalopathy arise. Understanding cirrhosis involves exploring its pathophysiology, systemic manifestations, diagnostic tools and management strategies. In this episode, Dr Roger Henderson discusses how chronic insults from viral hepatitis, alcohol or metabolic disease lead to progressive fibrosis, the development of portal hypertension and multisystem involvement.

Access episode show notes containing key references and take-home points at:

https://gpnotebook.com/en-GB/podcasts/gastroenterology/ep-195-liver-cirrhosis.

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