To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked to replace yeast’s native chromosomes with synthetic versions. This project has turned out to be an international collaboration, with some artistic endeavors along the way. Eventually, the goal is to create an entirely human-generated yeast genome. Links from this episode: <ul><li><a href='http://jointgeno.me/proposals'>Submit your own proposal to work with the JGI</a></li><li><a href='http://jointgeno.me/JGI2023'>Join us at the 2024 JGI User Meeting</a></li></ul> <ul><li><a href='https://jgi.doe.gov/genome-insider-s5-episode-3'>Episode Transcript</a></li><li>Paper: <a href='https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00852-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276523008523%3Fshowall%3Dtrue'>Manipulating the 3D organization of the largest synthetic yeast chromosome</a></li><li>NYU Release: <a href='https://nyulangone.org/news/researchers-assemble-nine-synthetic-yeast-chromosomes'>Researchers Assemble Nine Synthetic Yeast Chromosomes</a></li></ul> <ul><li>Our contact info:<ul><li>X:<a href='https://twitter.com/jgi'> @JGI</a></li><li>Email: jgi-comms at lbl dot gov</li></ul></li></ul>

Gotta Catch 'Em Gall

Stories where genes and genomes are key to solving energy and environmental challenges. Hear diverse voices in science talk about their JGI-supported research to better understand — and harness — the superpowers encoded in plants, fungi, microalgae, environmental viruses, and bacteria to contribute to a more sustainable world.&nbsp;