Gen C
Gen C
CoinDesk
IOTA’s Karen O'Brien on The $35 Trillion Bet on Industrial Blockchain
32 minutes Posted Jan 27, 2026 at 6:26 pm.
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Show notes
IOTA CMO, Karen O’Brien reveals the high-stakes roadmap to transform the $35 trillion global trade industry from archaic paper systems into a frictionless, blockchain-powered infrastructure.
Karen O’Brien, CMO of IOTA, breaks down why the industry is finally hitting a much-needed trust reset, trading short-term hype for the work of fixing global trade. O’Brien touches on how she’s helping solve the $35 trillion "paper and email" bottleneck to create an invisible backbone for global supply chains—a true blockchain for machines.
- Links mentioned from the podcast: 
Karen's Twitter 
IOTA Website
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Sam Ewen, CoinDesk
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"Gen C" features host Sam Ewen. Executive produced by Uyen Truong.