From First Principles
From First Principles
Krishna Choudhary and Lester Nare
Hacking The Human Brain, Unlocking Our DNA, Unbreakable Diamonds & The Quantum Magician (EP. 5)
2 hour 9 minutes Posted Aug 26, 2025 at 10:00 pm.
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This week we break down four big stories—no PhD required.

Reading “inner speech”: Invasive brain–computer interfaces record neurons in motor cortex and decode attempted vs. inner speech into words. Results from Stanford even generalize to simple symbols and numbers. Cool science, huge privacy questions, and a proposed “brain password” to keep users in control.
What makes us human: UC San Diego highlights human accelerated regions (HARs)—genomic control switches (promoters/enhancers) that tune when and where genes are used. We revisit classic HAR examples and a new result connecting a specific HAR to brain development.
Diamonds get an upgrade: Scientists at HPSTAR (Beijing) grow stronger lab diamonds with clear industrial upside—from cutting tools to power electronics—and potential to reduce harmful mining incentives.
International Year of Quantum (2025): A fast retrospective on 100 years of quantum mechanics and how today’s quantum tech is reshaping computing, sensing, and materials.

Hosts: Lester Nare & Dr. Krishna Choudhary
Show: From First Principles Podcast