Moderator: Simone Vigneri (Bologna, Italy)Guest: Marshall Devor (Jerusalem, Israel)This episode explores the complex clinical features and neurobiology of phantom limb pain, highlighting key mechanisms such as maladaptive plasticity, ectopic discharges, and cortical reorganization. Prof. Marshall Devor shares expert insights into current challenges and future directions in the management of this uniquely human neuropathic pain condition.