Until the advent of highly effective CFTR modulator medications, cystic fibrosis was considered a pediatric disease, because most individuals did not survive into adulthood. Now, with more adults living with CF than children, priorities must change. In these interviews, we discuss what transitions to a longer life with CF entails: from pediatric to adult care; from the possibilities of motherhood and the need for family planning; from adulthood into older age and the infirmities common to all aging adults.

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