DDT Method Podcast — Peptides, Performance Enhancement and Advanced Protocols with Drew Donaldson
DDT Method Podcast — Peptides, Performance Enhancement and Advanced Protocols with Drew Donaldson
Drew Donaldson | Performance Enhancement Coach
The GLP-1 Guide Every Lifter Should Hear Before Starting | Jason Theobald
1 hour Posted Jul 22, 2026 at 11:30 am.
Where everyone gets GLP-1 use wrong1:36 Semaglutide vs. tirzepatide vs. retatrutide — the mechanism explained8:59 The female retatrutide cases — when the "strongest" drug backfires17:49 Mitigating Reta’s HRV and heart-rate cost23:15 The origin of the Slingshot Method27:29 Stacking fast-acting insulin with the slingshot32:02 The post-prep tapering protocol36:58 Menopause, HRT, and why it's the best GLP-1 use case46:27 Ancillary tools: metformin, berberine, Jardiance52:12 The GLP Mentor app + where to find JasonConnect with Jason:Scooby-U coaching (on the Mighty app) — or DM @ScoobyHealth on IGHRT & peptide clinic: https://advancedvitalityhrt.comSupplements: https://newethics.comGLP Mentor app (AI coaching for GLP-1 users) — Apple App StoreBooks on Amazon — search "Jason Theobald": The IBS Fallacy, GLP-1 for Seniors, Menopause guides, 5-Minute Mediterranean Cookbook for GLP Users
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Go deeper on the protocols → DDT Skool: https://www.skool.com/ddtmethodWork with a DDT Method coach → Apply: https://www.ddtmethod.com/applyJason Theobald (Scooby Health, Advanced Vitality HRT, GLP Mentor) joins the show for a full GLP-1 deep dive built specifically for people who train — not the general population. We break down the real mechanistic differences between semaglutide, tirzepatide, and retatrutide (and why stacking GIP with glucagon suppression changes everything), why retatrutide's aggressive fat-burning comes with a real cost — elevated heart rate, HRV crashing, and in some of Jason's female and perimenopausal clients, lost muscle instead of fat — and why the "strongest" drug isn't automatically the right one for your hormone profile. Jason also breaks down his own experience pairing GLP-1s with small-dose fast-acting insulin, his tapering protocol for coming off after hitting a goal, and why he considers GLP-1 + HRT one of the most underused combinations for menopausal and andropausal clients. Pulled from thousands of patient cases across his coaching business and his HRT clinic, this is the guide for anyone using — or considering — a GLP-1 as an athlete.KEY TAKEAWAYS:Why Semaglutide, tirzepatide, and retatrutide aren't interchangeableRetatrutide's triple mechanism burns fat fastest, but there’s a catch for some populationsThe real cost of retatrutide most people ignore and how Jason manages itJason's "Slingshot Method" to grow from GLPsThe best use case for GLP-1s and metabolic functionCHAPTERS:0:00 Where everyone gets GLP-1 use wrong1:36 Semaglutide vs. tirzepatide vs. retatrutide — the mechanism explained8:59 The female retatrutide cases — when the "strongest" drug backfires17:49 Mitigating Reta’s HRV and heart-rate cost23:15 The origin of the Slingshot Method27:29 Stacking fast-acting insulin with the slingshot32:02 The post-prep tapering protocol36:58 Menopause, HRT, and why it's the best GLP-1 use case46:27 Ancillary tools: metformin, berberine, Jardiance52:12 The GLP Mentor app + where to find JasonConnect with Jason:Scooby-U coaching (on the Mighty app) — or DM @ScoobyHealth on IGHRT & peptide clinic: https://advancedvitalityhrt.comSupplements: https://newethics.comGLP Mentor app (AI coaching for GLP-1 users) — Apple App StoreBooks on Amazon — search "Jason Theobald": The IBS Fallacy, GLP-1 for Seniors, Menopause guides, 5-Minute Mediterranean Cookbook for GLP Users