Episode 46 of CRAMSURG - Clinical Research Appraisal and Methodology for Surgical Trainees. The paper for discussion is Laparoscopic liver resection versus radiofrequency ablation for small hepatocellular carcinoma: randomized clinical trial BJS Apr 2024. The teaching topic is multi arm RCTs part 3 - master protocols. Brought to you by CRAMSURG www.cramsurg.org.