Clinical decision support systems are IT-based tools that compile patient- and context-specific data, presenting this to providers at the point-of-care and clinical decision making. These systems are an excellent means for pathologists to influence laboratory test-ordering practices and to foster appropriate test use. However, the optimal methods to design, implement and maintain CDSS are not well-known, representing an important gap in knowledge, explains Dr. Amanda Blouin in this CAPcast interview. Dr. Blouin, a pathologist at Memorial Sloan Kettering in New York City, will be teaching a course on this topic with Dr. Ronald Jackups at CAP20, which will be held virtually this year from Oct. 10-14. For more information about CAP20, visit www.capannualmeeting.org and follow #cap20virtual on social media.