In this episode of Cancer Luminaries, host Camilla Frost-Brewer speaks with Dr. Maryellen Giger and Dr. Alex Pearson about how AI and machine learning are transforming cancer research and care at UChicago. They discuss the long history of AI in medical imaging, the rise of tools like large language models in clinical workflows, and the promise of AI to improve diagnostics, precision medicine, and patient care. The conversation also highlights the importance of equity, transparency, and thoughtful design as these technologies are integrated into the future of oncology.