Broken Brain with Dhru Purohit
Broken Brain with Dhru Purohit
Dhru Purohit, Dr. Mark Hyman
The Broken Brain podcast will help you take your brain health to the next level and teach you how to live your best life! Listen as host and serial entrepreneur Dhru Purohit interviews the top experts in the field of neuroplasticity, epigenetics, biohacking, mindfulness and functional medicine. See for privacy and opt-out information.
#84: How Out of Control Blood Sugar Contributes to Body Fat, Brain Fog, and Alzheimer's with Dr. Ronesh Sinha
1 hour 31 minutes Posted Dec 13, 2019 at 3:00 am.
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    Excess insulin and chronic inflammation are powerful threats to our health and longevity, and the underlying thread that weave together virtually every chronic disease. On today’s Broken Brain Podcast, our host, Dhru, talks to Dr. Ronesh Sinha, an internal medicine physician in Silicon Valley who works for the Palo Alto Medical Foundation and serves as director for employer wellness, strategy, and product development. He has designed successful health education and wellness programs for over 20 major Silicon Valley companies, launched a medical mobile clinic providing primary care to busy employees, and developed a dedicated consult practice geared to Asians and Indians with insulin resistance and related conditions.His groundbreaking work in reversing diabetes in culturally diverse populations has received global attention with front cover stories in Fortune Magazine and the LA Times, and earned him the Silicon Valley Business Journal’s Excellence in Healthcare award. Dr. Sinha blogs actively on health at, and hosts a popular Bay Area weekly radio show on health. He is passionate about developing innovative, culturally tailored solutions to help diverse populations lead healthier lives. He is also the author of The South Asian Health Solution. In this episode, Dhru and Dr. Sinha discuss what insulin resistance is, why it matters to your health, what happens when insulin resistance persists, and the impact it has on your brain. They talk about the role of ethnicity on insulin resistance and metabolism, and how a sedentary lifestyle impacts insulin resistance. They also talk about the difference between visceral fat and subcutaneous fat, and the lifestyle changes we can implement to address insulin resistance, metabolic dysregulation, and inflammation. In this episode, we dive into:-How insulin resistance impacts our health (1:41)-The connection between insulin resistance and Alzhiemer’s (6:07)-Adaptive insulin resistance vs. chronic insulin resistance (10:47)-Metabolic syndrome and the role triglycerides play in the body (14:03) -The impact of insulin resistance when is comes to specific cultures (29:33)-The connection between a sedentary lifestyle and insulin resistance (35:48)-The hidden danger of being “skinny fat” (39:29) -Statins vs. lifestyle interventions for treating insulin resistance (49:41)-How sleep impacts insulin resistance (59:34)-Fasting and insulin resistance (1:02:02) -Where to learn more about Dr. Ronesh Sinha (1:24:35)For more on Dr. Ronesh Sinha, be sure to follow him on Instagram @roneshsinhamd. Check out his website, and his innovative education and wellness programs at You can find his book, The South Asian Health Solution: A Culturally Tailored Guide to Lose Fat, Increase Energy and Avoid Disease, right here. Lastly, you can learn more about Dr. Sinha’s 8-week online Whole Family Health program that focuses on individuals and families who want to prevent or reverse conditions involving insulin resistance and/or inflammation here: This episode is sponsored by our partnership with the AquaTru Water Filter. To get exclusive access to this deal visit See for privacy and opt-out information.