Dr. Stephen Gomperts gives an overview of the Lewy body dementias, the second most common neurodegenerative dementia after Alzheimer’s, affecting some 1.4 million Americans. He explains that there are two clinically distinct but related diseases: dementia with Lewy bodies, also known as DLB, and Parkinson’s dementia. He explains the clinical features, the diagnostic process, and treatment strategies. He advocates a team approach to caring for these complex diseases that affect cognitive, physical, and behavioral functions.