While many diseases are now known to have genetic components, many of the specific mutations involved are unknown in 60-70% of patients.

Our DNA contains vast non-coding regions that Uirá Melo likens to dark matter in the universe - we know it's there but what does it do in these diseases?

Now, thanks to new technologies in genome sequencing, he is working at the Max Planck Institute in Berlin to sort through this DNA dark matter from an array of patients.

In this Episode, Uirá explains his work illuminating the darkness in DNA and how he decided to become an entrepreneur on his journey from Brazil to Berlin.