Non coding RNA may regulate melanogenesis and in combination with plasma cell producing IgG the nutritional regulation of satiety.
Aging results in alterations of this complex system thus resulting in localized melanogenesis and a corruption of the HPA axis.
References:
Aging (Albany NY). 2021 Jan 31; 13(2): 2700–2726.
Stem Cells Int. 2020; 2020: 1047896. First Published online 2020 Jul 8
PNAS. 2002 Dec 24;99(26):17155-60
 

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Membrane Biochemistry Primer and Introduction to Aging. Dr. Daniel J. Guerra. Authentic Biochemistry Productions. 13.9.21

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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.