<p>Dr Daniel Guerra or VerEvMed and AB podcast provides the second part of his discussion concerning excitotoxic glutamate inducing aSMASE mediated neurodegeneration involving iron and the depletion of the glutathione-ROS- scavenging system in damaged and diseased oligodendrocytes. 25March2019B</p>

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HDAC 4 is a positive player in ALS muscle since it is not a functional histone deacetylase: The complexity of motor neuron disease reveals not-so-subtle differences in protein function

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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.

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Dr Daniel Guerra introduces a novel PCD pathway- ferroptosis- that is  linked to excitotoxicity and lipid peroxidation leading to neurodegeneration. Part I

Dr Guerra continues : Glutamate induced ferroptosis involves lipid peroxidation and ceramide production leading to an inflammatory response in neurodegeneration