GLP-1s in Addiction Medicine: An Update Since Our Last Conversation from ASAM Practice Pearls

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GLP-1s in Addiction Medicine: An Update Since Our Last Conversation

33 minutes Posted Aug 24, 2026 at 9:00 am.

Introduction

Latest Developments in Research

Prescribing GLP-1’s Off Label

Challenges With Prescribing

Who Benefits From GLP-1’s and Who Doesn’t

Potential for Other SUD Treatment Beyond AUD

Side Effects, Tolerability Concerns, and Adherence Challenges

Where GLP-1’s Fit into the Treatment Toolbox

Unanswered Questions about GLP-1 Treatment

GLP-1’s Possible Impact on Mood

Dosing Strategy and Titration Approach

Life After GLP-1s: Rebound Risk and ”Chipping”

Biggest Surprise from the Research So Far

Practice Pearls

Conclusion and Additional Learning Opportunities

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Show notes

In this episode of ASAM Practice Pearls, Dr. Stephen Taylor welcomes back Dr. Stephanie Weiss and is joined by Dr. Anna Lembke to explore an update on GLP-1 receptor agonists for alcohol use disorder (AUD), discussing current research, how things have evolved since the last discussion, and the challenges and implications of integrating these innovative treatments into addiction care.

← See all 37 episodes of ASAM Practice Pearls