Motorneurone Disease (MND), which is also known as ALS and Lou Gehrig's Disease, is caused by the death of the motor nerves that convey movement instructions from the nervous system to muscles. We don't understand why this happens, but up to 10% of cases appear to be genetic. Now Babraham Institute researcher Jemeen Sreedharan has genetically engineered into a mouse the same genetic change that causes MND in humans. His animals are now providing us with new insights into the pathological process that underlies MND, as he explains to Chris Smith...Jameen - Motorneurone disease is an... Like this podcast? Please help us by supporting the Naked Scientists