This Week in Startups
This Week in Startups
Jason Calacanis
Ask Jason: AI Extinction, Grok's Rogue Meme Coin & Weed Farms as Data Centers | E2337
1 hour 11 minutes Posted Sep 14, 2026 at 9:13 pm.
(Question) Jim, from the midterm Republican convention floor: is AI really going to kill us all — and is local AI the mitigation?
Where Terminator 2's logic breaks down
The threat Jason is actually scared of: slaughter drones and murder bots
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(Question) Michael Lee, who's responsible when one AI prompts another into launching a meme coin?
(Question) Lyda, calling from Greece: can an independent AI ecosystem still exist
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(Question) John Wright: do you have to carve out more time now just to keep up with the tools?
Claude's caution vs. Grok's "hold my beer"
(Question) John Wright, part two: do you expect founders to get more done now
The three buckets: 10x, 5x, and the 20% crowd
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(Question) Ray, Vortex Console: can human-in-the-loop actually work at enterprise scale?
(Question) Kristen Dahl: how do you explain AI risk to your 76-year-old mom?
Why the chaos only happens at OpenAI and Anthropic
(Question) David Rosenberg, NYU physics: what's behind the academic backlash to AI solving Navier-Stokes?
Advice for a 20-year-old: find two smart people, build weird things
(Question) David's follow-up: any chance of an All-In Summit scholarship
(Question) Mo: can a cannabis cultivation facility be converted into a data center
(Question) Mo's follow-up: Mark Cuban's pickleball courts and the efficiency curve
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Today's show:
A 27-year-old Anthropic researcher quit last week warning that AI could cause human extinction, and by Friday, a caller's 76-year-old mother was texting her in a panic. Jason's answer: the labs are already shipping the safeguards Doomers say don't exist.
On an all live calls episode of TWiST, learn about the AI implications Jason is actually scared of, and why it involves a terrorist cell and a thousand cheap drones. PLUS, who is liable when one AI prompts another AI into launching a meme coin, and can a 1.5-3 megawatt cannabis facility be converted into a data center?
Relevant Links:
Anthropic Resignee — https://www.nbcnews.com/tech/tech-news/anthropic-safety-researcher-resigned-warning-rapid-ai-development-gamb-rcna596767
OpenAI's Navier-Stokes claim— https://www.science.org/content/article/how-ai-math-breakthrough-ignited-controversy
CNBC: Tristan Buckmaster's challenge to the claim — https://www.cnbc.com/2026/09/09/openai-navier-stokes-math-problem-solved.html
NVIDIA GB200 Grace Blackwell —https://www.nvidia.com/en-us/data-center/gb200-nvl72/
Composio's walkthrough of how Grok Bot actually works — https://composio.dev/content/guide-to-frok-bot
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