Theories of Everything with Curt Jaimungal
Theories of Everything with Curt Jaimungal
Theories of Everything
Adrian Owen: Awake. Aware. Unable to Move.
1 hour 33 minutes Posted Aug 24, 2026 at 2:56 pm.
Trapped Consciousness Detection
Total Locked-in Syndrome
Wakefulness Without Awareness
The fMRI Tennis Test
Decoding Neural Intent
Mapping the Grey Zone
Non-Responsive Patient Lucidity
Life-Support Ethical Dilemmas
Brain-Computer Interface Futures
Hijacking Consciousness via Narrative
The Liam Neeson Test
Thalamocortical Pathway Disruption
Deep Brain Stimulation Potential
Anesthetic Awareness Dangers
AI and Language Lures
IIT Pseudoscience Controversy
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There are three questions people ask about consciousness: what it is, how to explain it, and how to measure it. This episode is entirely the third one. Adrian Owen, professor of cognitive neuroscience at Western University, joins to explain how he detects consciousness in patients thought to be completely unaware — and why he believes thousands have been "hiding in plain sight" for decades. Owen walks through the landmark case that started it all: asking a non-responsive patient to imagine playing tennis, and watching her brain light up like a healthy person's. We discuss the differences between coma, vegetative state, minimally conscious state, and locked-in syndrome, and what recovered patients have reported about their experience — including one man whose memories were sharper than his doctor's. The conversation covers how movies like Taken are used to detect awareness through brain synchronization, why negative results can never prove someone is unconscious, and the ethics of asking a locked-in patient if they want to keep living. This is an in-depth conversation with Adrian Owen.
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LINKS MENTIONED:
- The Owen Lab: https://owenlab.org/
- Think Before You Think [Book]: https://amazon.com/dp/1324075163?tag=toe08-20
- Into The Gray Zone [Book]: https://amazon.com/dp/1501135201?tag=toe08-20
- Into The Gray Zone [Lecture]: https://youtu.be/01_ECXZK9dA
- Detecting Awareness In The Vegetative State [Paper]: https://www.science.org/doi/10.1126/science.1130197
- Cortical Processing In Persistent Vegetative State [Paper]: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)77805-3/abstract
- Response To 'Minimally Conscious State Or Cortically Mediated State?' [Paper]: https://academic.oup.com/brain/article/141/4/e26/4838964
- Risk, Diagnostic Error, And The Clinical Science Of Consciousness [Paper]: https://pubmed.ncbi.nlm.nih.gov/25844313/
- A Common Neural Code For Similar Conscious Experiences In Different Individuals [Paper]: https://www.pnas.org/doi/10.1073/pnas.1407007111
- Locked-In Syndrome: https://www.ninds.nih.gov/health-information/disorders/locked-syndrome
- CIFAR: https://cifar.ca/research-programs/brain-mind-consciousness/
- Tests For Consciousness In Humans And Beyond [Paper]: https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(24)00010-X
- Early Identification Of Recovery Potential After Acute Brain Injury Using Functional Near Infrared Spectroscopy [Paper]: https://link.springer.com/article/10.1007/s12028-026-02605-0
- Consciousness Iceberg [TOE]: https://youtu.be/65yjqIDghEk
- Michael Levin & Anil Seth [TOE]: https://youtu.be/_kuwwmFnxGY
- Iain McGilchrist [TOE]: https://youtu.be/Q9sBKCd2HD0
- Roman Yampolskiy [TOE]: https://youtu.be/TgFmA-Qwsek
- Elan Barenholtz [TOE]: https://youtu.be/A36OumnSrWY
- Simon Saunders [TOE]: https://youtu.be/Ihv542rCUns
Guests do not pay to appear. #science
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