Today, we have a metabolic health masterclass, featuring Dr. Robert Lustig, Ben Azadi, Dr. Ben Bikman, Mark Sisson, and Dr. Nick Norwitz. In today’s masterclass, we explore why metabolic dysfunction is not simply a calories-in, calories-out issue or a failure of willpower, how insulin and leptin influence appetite and behavior, how early signs of insulin resistance can appear years before a diabetes diagnosis, and the important relationship between muscle, glucose regulation, and insulin sensitivity. We also discuss how movement supports fat burning without sacrificing muscle, why chronic cardio may not produce the results many people expect, and how emerging technology could provide a far more personalized approach to metabolic care.Stay tuned for today’s informative discussion, where our panel of experts shares their valuable perspectives on metabolic health.IN THIS EPISODE, YOU WILL LEARN: Leptin resistance and how it can drive the overeating and inactivity commonly associated with obesity How elevated insulin blocks the effects of leptin Why it’s essential to pay attention to fasting insulin rather than waiting for blood glucose to rise  Ben Azadi highlights metabolic health markers that can provide information beyond fasting glucose. How our muscles help to regulate glucose and support insulin sensitivity The importance of building and preserving muscle to support insulin sensitivity as we age, and how even a brief period of inactivity can reduce insulin sensitivity Mark Sisson explains why running may not be the most effective fat loss strategy  How walking can increase your fat-burning capacity while also helping to preserve your muscles Dr. Nick Norwitz explains how type 2 diabetes can involve different underlying pathologies, and how CGM data and machine learning can eventually help to identify specific subphenotypesConnect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected]  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement LineConnect with Dr. Robert LustigWebsite On Facebook, Instagram, and Twitter Connect with Ben AzadiWebsiteOn Instagram, Facebook, LinkedIn, YouTube, TikTokGet a copy of Ben Azadi’s latest book, Metabolic Freedom.Connect with Dr. Ben BikmanWebsiteOn social media: @benbikmanphdConnect with Mark Sisson  Mark’s book, Born To Walk Peluva ShoesConnect with Nick NorwitzOn YouTube, X, and InstagramHis SubstackPrevious Episodes:Ep. 161 Robert Lustig & Cynthia Thurlow Discussing The Nutritional Battlefield & Debunking Chronic DiseasesEp. 465 Metabolic Health 101: Fat Loss, Toxins, and Seed Oils with Dr. Ben AzadiEp. 316 The Impact of Age, Gender and Lifestyle on Metabolic Health with Dr. Ben BikmanEp. 422 Walking for Health: The Underrated Exercise You Need with Mark SissonEp. 525 We’ve Been Misled About Metabolic Health – The Shocking Truth About Cholesterol, GLP-1 & Aging with Dr. Nick Norwitz