Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+
Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+
Everyday Wellness™
Ep. 596 “When Estrogen Drops, Your Gut Feels It” – How Hormones Slow Digestion in Midlife | Menopause, Perimenopause & Gut Health
25 minutes Posted May 21, 2026 at 7:00 am.
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Show notes
Welcome to today’s Midlife Minute.
Today, we’re exploring bloating, constipation, and various other midlife gut woes. 
Stay tuned as I clarify how midlife changes the gut narrative and review the evidence about how to get things moving again.
IN THIS EPISODE, YOU WILL LEARN:
Why your gut motility changes in midlife
How menopause influences the gut-brain connection
Why various types of constipation require different interventions
How changes in your gut bacteria affect the way your gut functions in menopause
How different types of fiber can either help or worsen constipation symptoms, depending on the type of constipation 
The main types of constipation, and how they differ 
How estrogen therapy may influence bowel regularity, and why the route of administration matters
Lifestyle habits that can stimulate bowel movements
Why bloating tends to occur in midlife
Connect with Cynthia Thurlow  
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. 
Cynthia’s Menopause Gut Book is on presale now!
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Links:
1. Menopause Is Associated with an Altered Gut Microbiome and Estrobolome, with Implications for Adverse Cardiometabolic Risk in the Hispanic Community Health Study/Study of Latinos
2. The Intestinal Microbiome and Estrogen Receptor–Positive Female Breast Cancer 
3. Estrogen–gut microbiome axis: Physiological and clinical implications
4. Menopausal shift on women’s health and microbial niches
5. Gut microbiota has the potential to improve health of menopausal women by regulating estrogen
6. Gut-microbiota-targeted diets modulate human immune status
7. Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in postmenopausal women
8. Constipation and diarrhea during the menopause transition and early postmenopause: observations from the Seattle Midlife Women’s Health Study
9. Estrogen Rather Than Progesterone Cause Constipation in Both Female and Male Mice
10. Rome IV Criteria
11. Gut-Directed Hypnotherapy for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis 
Gut-Directed Hypnotherapy for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis (PubMed)
12. Randomised clinical trial: the efficacy of gut-directed hypnotherapy is similar to that of the low FODMAP diet for the treatment of irritable bowel syndrome
13. Gut-directed hypnosis and hypnotherapy for irritable bowel syndrome: a mini-review
14. Review article: gut-directed hypnotherapy in the management of irritable bowel syndrome and inflammatory bowel disease